noun
senior; upperclassman; older colleague
Slang reversal of 先輩 (せんぱい). Used playfully or casually among friends, often by younger people. Can sound cheeky or affectionate depending on context.
See also: 先輩 (せんぱい)
パイセン、今日もお疲れっす!
Hey senior, thanks for your hard work today!
あのパイセン、めっちゃ面白いんだよね。
That upperclassman is really funny.