どうしたって

adverb

no matter what; by all means; at any rate

Colloquial expression of strong determination or inevitability, similar to どうしても but more casual. Often used when insisting that something will happen or must be done regardless of obstacles.

See also: 如何しても

• どうしたって明日あしたまでに終おわらせなきゃ。

  No matter what, I have to finish it by tomorrow.

• どうしたって彼かれには勝かてないよ。

  There's no way I can beat him, no matter what.