four-panel comic strip; yonkoma
Abbreviation of 四コマ漫画. Refers to the format itself or a single strip; very common in manga and newspaper contexts.
See also: ４コマ漫画
I look forward to the newspaper's four-panel comic every day.
He draws four-panel comics as a hobby.
Abbreviation of 四コマ漫画 (four-panel comic). 四 (four) + コマ (panel/frame).