pronoun
His Holiness; Your Holiness
Christian honorific title used for the Pope or other high-ranking religious figures. Can be used as a form of address (Your Holiness) or in reference (His Holiness).
聖下はバチカンで演説をされた。
His Holiness gave a speech at the Vatican.
聖下、お目にかかれて光栄です。
Your Holiness, it is an honor to meet you.