A fluid-filled bubble on the skin caused by friction, burns, or irritation. Common in everyday conversation.
I got a blister on my heel from walking in new shoes.
When you get a blister from a burn, it's better not to pop it.
Most common spelling; uses kana for ぶくれ to avoid rare kanji.
Kanji spelling using 膨れ (swelling); less common but still used.
Rare variant using 脹れ (swelling); mostly seen in older texts.
Compound of 水 (water) and 膨れ (swelling, blister). The reading みずぶくれ is a straightforward combination of the kun'yomi readings of the components.