noun, used as a suffix
sis; dependable woman
Internet slang derived from あねき (姉貴). Used as a suffix to refer to a woman one respects or relies on, similar to 'sis' or 'big sis' in English online communities. Often attached to names or handles.
あのネキ、いつも相談に乗ってくれるんだよね。
That sis always gives me advice.
配信者のネキが今日も面白い。
The streamer sis is funny again today.