お変かわりありませんか

expression

How have you been?; Is everything all right?

Polite greeting used after some time apart, asking if anything has changed or if everything is well. Often used in letters or when meeting someone after a while.

• お久ひさしぶりです。お変かわりありませんか。

  It's been a while. How have you been?

• その後ご、お変かわりありませんか。

  I hope everything has been well with you since then.