Wasei-eigo from English 'Mister lady'; refers to a person assigned male at birth who dresses and presents in a feminine manner. The term is somewhat dated and may be considered insensitive in modern contexts; トランスジェンダー or 女装家 are more current alternatives.
wasei-eigo (Japanese-coined English), from Mister lady
In old TV shows, the term 'Mister Lady' was sometimes used.
Variant with interpunct; less common but still seen.
Japanese-coined English from Mister lady, formerly used for a transvestite or cross-dresser.