degenerative disease
Medical term for a disease characterized by progressive deterioration of tissue or organ function.
Alzheimer's disease is one of the typical degenerative diseases.
In many cases, treatments for degenerative diseases have not yet been established.
慢性疾患 (chronic disease) refers to a long-lasting condition, while 変性疾患 specifically involves progressive degeneration.
neurodegenerative disease; neurodegenerative disorder
Compound of 変性 (degeneration) and 疾患 (disease). The exact historical derivation is uncertain; the term is a modern medical coinage.