expression, suru verb (irregular)
bring to nothing; waste; abuse
Used for rendering something useless, wasting an effort or opportunity, or taking advantage of someone's kindness. Often with objects like 努力, 好意, チャンス.
彼の努力を無にするようなことをしてはいけない。
You mustn't do anything that would bring his efforts to nothing.
せっかく
I wasted a precious chance.
expression, suru verb (irregular)
Used in the pattern 〜を無にする to mean making something empty or clearing it, especially the mind (心を無にする).
瞑想するときは心を無にすることが大切だ。
When meditating, it's important to empty your mind.