pronoun
you (polite, slightly familiar)
Polite second-person pronoun with mild familiarity; used when addressing someone with light respect, such as a neighbor or acquaintance. Less formal than あなた, but warmer than a title.
See also: お宅
おたくさん、最近お元気でしたか。
How have you been lately?
おたくさんのご主人はお元気ですか。
Is your husband doing well?