conjunction
and yet; but even so; nevertheless
Expresses a contrast with what was just said, often with a feeling of surprise, disappointment, or frustration. Similar to それでも but with a stronger sense of 'despite that being the case'.
彼は一生懸命勉強した。それなのに、試験に落ちてしまった。
He studied very hard. And yet, he failed the exam.
The weather forecast said it would be sunny. But even so, it suddenly started raining.