Used to indicate that something doesn't matter or that one is indifferent; often in phrases like どうでもいい (it doesn't matter) or どうでもする (do as one likes).
That doesn't matter at all.
by all means; at any cost; no matter what
Expresses strong determination to achieve something regardless of difficulty; often used with verbs like する or なる.
Do as you like.
I want to see him no matter what.
I'll make it succeed by all means.