キリキリ

〈体からだの部ぶ分ぶん〉がキリキリ痛いたむfor a body part to hurt with a sharp, stabbing pain
緊きん張ちょうすると胃いがキリキリ痛いたむ。
When I get nervous, my stomach hurts with a sharp, stabbing pain.
〈物もの〉をキリキリ締しめるto pull or tighten something firmly and tensely
ロープをキリキリと締しめて荷に物もつを固こ定ていした。
I pulled the rope tight and secured the luggage.
歯はをキリキリ鳴ならすto grind one's teeth (making a sharp grinding sound)
彼かれは寝ねている間あいだに歯はをキリキリ鳴ならす。
He grinds his teeth while he's sleeping.
〈物もの〉がキリキリ回まわるfor something to spin around rapidly (often with a whirring sound)
風かざ車ぐるまがキリキリと勢いきおいよく回まわっている。
The pinwheel is spinning around rapidly.
キリキリ働はたらくto work briskly and efficiently
彼かの女じょは朝あさからキリキリと働はたらいている。
She has been working briskly since morning.

Related words

ぎゅっと sense 2
キリキリ describes winding or pulling something tight with a sense of tension or creaking, while ぎゅっと simply describes a firm, single squeeze or grip.
くるくるN1sense 3
キリキリ describes fast, sometimes creaking spinning, while くるくる is the more neutral word for something turning round and round.
しくしくN1sense 4
キリキリ describes a sharp, stabbing pain (as in a stomach ache), while しくしく describes a dull, lingering ache.
きびきびN2sense 5
キリキリ working suggests brisk activity with a slight sense of pressure or urgency, while きびきび emphasizes crisp, energetic movement without that tension.
ずきずきN1
きりきり describes a sharp, twisting or cramping pain (often in the stomach), while ずきずき describes a throbbing, pulsing pain.

ぎりぎり
キリキリ and ギリギリ sound alike, but キリキリ describes grinding, binding, or sharp pain, while ギリギリ usually means 'barely' or 'right at the limit'.

Mimetic word; the exact origin is uncertain, but it is likely sound-symbolic, imitating a sharp, continuous sound or sensation.