noun
Refers specifically to a shop dealing in old art objects and antiques, not just any second-hand goods.
この古美術店で江戸時代の掛け軸を見つけた。
I found an Edo-period hanging scroll at this antique store.
骨董品店 is a more general term for an antique shop, while 古美術店 emphasizes old art objects.
Compound of 古 (old), 美術 (art), and 店 (shop).