noun
de novo mutation
A genetic term for a mutation that appears for the first time in a family, not inherited from either parent.
この病気は新生突然変異によって起こることがある。
This disease can be caused by a de novo mutation.
Compound of 新生 (new, novel) and 突然変異 (mutation). The term is a direct translation of the English 'de novo mutation' used in genetics.