noun
butting in; off-topic reply; interjecting in a thread
Internet slang for replying to a discussion thread or message board conversation with an unrelated or unsolicited comment, or the reply itself. Often used when someone jumps into a conversation without invitation.
スレの流れと関係ない横レスはやめてください。
Please stop making off-topic replies that have nothing to do with the thread.
彼の横レスで話が脱線した。
The conversation got derailed by his interjection.