expression, godan verb (-ru)
lose one's virginity (of a woman); become sexually active (of a woman)
Euphemistic expression used specifically for a woman's first sexual experience with a man. Often carries a slightly literary or old-fashioned tone.
彼女はまだ男を知らないと言っていた。
She said she hasn't been with a man yet.
あの小説の主人公は、
The protagonist of that novel loses her virginity while traveling.