missus; wife (of a shopkeeper, landlord, etc.)
Familiar, somewhat old-fashioned term for a married woman, especially the wife of a shopkeeper, landlord, or master. Originally an honorific, now used in casual or friendly address. Often written in kana.
The missus next door is always kind to me.
The wife of that shop is very friendly.
おかみさん is a traditional term for the proprietress of a shop, inn, or restaurant, while ママさん specifically refers to the owner of a bar or snack club.
Kanji form using 上; less common than kana.
Rare kanji form using 内儀; may be encountered in older texts.
Derived from 御上 (okami, 'honorable above') with the honorific さん, originally a respectful term for a superior's wife. The exact historical development is uncertain.