Commonly used in compound nouns like レスキュー隊 (rescue squad) or レスキュー活動 (rescue operations).
A helicopter flew to rescue the people stranded in the mountains.
He is active as a member of a rescue squad.
The fire brigade rescued the climber who got into trouble on the mountain.
A helicopter headed out to rescue the disaster victims.
Rescue operations were carried out in the flood-hit area.