older brother and his wife
Refers to one's own older brother and his wife as a unit. Used when talking about the couple together.
兄夫婦は来月、新居に引っ越すそうです。
I hear my older brother and his wife are moving to a new house next month.
Compound of 兄 (あに, 'older brother') and 夫婦 (ふうふ, 'married couple').