Describes matters, affairs, or conditions within a single country, as opposed to international or foreign. Often used in news, politics, and economics.
This issue is a domestic matter.
Domestic demand is increasing.
国際的 means 'international', the opposite of 国内的.
国内的 describes something confined to domestic affairs, the opposite of 国際的 which crosses national borders.
Compound of 国内 (domestic, within the country) + 的 (suffix forming adjectival nouns).