Refers to a physically huge person or a person of outstanding achievement. The 'great man' nuance is often used in historical or literary contexts.
He is as big as a giant.
He is a giant in the music world.
The Giants won the championship this year.
I've been rooting for the Giants ever since I was a kid.
巨人軍 is the full formal name of the Yomiuri Giants, while 巨人 is the everyday short form used in casual speech and headlines.
巨匠 specifically praises someone as a master of an art or craft, whereas 巨人 more broadly means a giant figure, physical or metaphorical.
巨人 literally means a giant or huge figure, while モンスター is used more broadly and metaphorically for a person or thing of extraordinary size, power, or influence.
巨人 is the native Japanese word for a giant being, while ジャイアント is the katakana loanword with a more commercial or fantasy flavor.
巨人 can refer to a mythical or legendary giant, or figuratively to a great person, whereas 巨漢 always describes a real man's exceptionally large physique.
From Middle Chinese 巨人 (giant). The kanji 巨 means 'huge' and 人 means 'person'.