He played the villain in that movie.
会議で彼は悪役を買って出た。
He took on the role of the bad guy at the meeting.
He is good at playing the villain in dramas.
He deliberately played the villain during the negotiation.
A famous actor took on the villain's role in that movie.
悪役 means 'villain', the role opposite the ヒロイン in a story.