noun
Polite everyday word for a skin eruption such as a boil, blister, or pimple. Often used in family or clinical contexts.
See also: できもの
顔におできができて痛い。
I got a pimple on my face and it hurts.
おできができたら、つぶさないでください。
If you get a boil, please don't squeeze it.
できもの is a more general and clinical term for any skin growth or eruption, while おでき is a softer, everyday word often used for boils or pimples.
Polite prefix お + でき (from できる, 'to form, appear'), referring to something that has formed on the skin.