にしても
Meanings
even if; even though; even granting that
Concessive expression meaning 'even if/though'. Used with verbs, adjectives, or nouns to acknowledge a condition while stating that the main point still holds.
Even if it rains, the game will probably be held.
Even if he comes, I don't think he'll come right away.
Follows a noun to mean 'even' or 'also', often implying that something is true for that noun as well as others. Similar to も but with a slight concessive or emphatic nuance.
Even he would say the same thing.
This problem is difficult even for experts.
Used in the pattern ...にしても...にしても to list alternatives, meaning 'whether ... or ...'. Both options lead to the same conclusion.
Whether you go or not, you need to contact them.
Whether it's a dog or a cat, keeping a pet comes with responsibility.
no matter (what, where, who, etc.)
Follows an interrogative word (e.g., 何, どこ, 誰) to mean 'no matter what/where/who'. Emphasizes that the statement holds regardless of the specific answer.
No matter who you are, this job is tough.
No matter what you do, planning is important.