noun
neurosis; nervous breakdown; mental health issue
A broad, somewhat dated term for a range of mental or emotional disturbances, including anxiety, obsession, or identity crisis. In modern Japanese, more specific clinical terms are often preferred, but ノイローゼ remains common in everyday speech for describing a state of mental strain or a 'nervous breakdown'.
from German Neurose
仕事のストレスでノイローゼになりそうだ。
I feel like I'm going to have a nervous breakdown from work stress.
彼は長い間ノイローゼに悩まされていた。
He suffered from neurosis for a long time.