Honorific term used to refer to or address one's own older brother with respect. Often used in formal or traditional contexts, such as samurai or historical settings. In modern casual speech, お兄さん or 兄貴 are more common.
My honored older brother departed for Edo today.
Honored brother, did you call for me?
Compound of 兄 (ani, 'older brother') and 上 (ue, 'above'), literally 'brother above'. The suffix 上 is an honorific indicating respect and elevated status.