something unusual; something wrong; mishap
Almost always used in negative expressions like 別条なく or 別条がない to mean 'nothing unusual/wrong' or 'no change for the worse'. The literal meaning 'different situation' is rare.
The test results showed nothing wrong with my body.
He remained conscious after the accident and his life is reportedly not in danger.
He continues working without any problems.
There's nothing wrong with his recovery after the surgery.