good-for-nothing; nuisance; troublemaker
Refers to a person who causes trouble or is useless; often used in a mildly scolding or exasperated tone.
That guy is a real nuisance.
My younger brother is always treated as a troublemaker at school.
Compound of 困り (from verb 困る 'to be troubled') + 者 ('person'). Literally 'a person who causes trouble'.