there is no God!; it's a cruel world
An exclamation of despair or indignation at the lack of divine justice or mercy in the world. Literally 'there is no god or Buddha'.
To suffer like this... there is no God!
For such a good person to die... it's a cruel world.
A set phrase combining 神 (god) and 仏 (Buddha) with the negative ない, expressing the absence of divine compassion. The exact origin is uncertain, but it reflects a traditional Japanese worldview where both Shinto and Buddhist deities are invoked.