Used primarily in compounds such as 致命的 (fatal, deadly) or 致命傷 (fatal wound). Rarely used as a standalone noun.
The accident was fatal for him.
This mistake could be a fatal blow.
fatal wound; mortal injury
fatal; lethal; deadly
case fatality rate
new martyr; neomartyr
From 致 (bring about, cause) and 命 (life), literally 'to cause loss of life'. The exact historical derivation is uncertain, but the compound has been used in Japanese to mean 'fatal' since at least the early modern period.