roadblock; road closure
Refers to the act of blocking or closing a road, often for security, construction, or events.
The police set up a roadblock at the accident scene.
A road closure will be carried out from tomorrow due to construction.
通行止め is a more common, everyday term for 'road closed' or 'no thoroughfare', while 道路封鎖 often implies a deliberate blockade or closure for a specific purpose.
Compound of 道路 (road) and 封鎖 (blockade, closure).