Polite term for a commercial establishment; often used when speaking respectfully about someone else's business or in customer service contexts.
See also: 店
I'm planning to open a shop near the station next month.
The cakes at that shop are very delicious.
Excuse me, is there a store nearby?
She runs a small café shop.
When I was a university student, I worked at that shop.
I didn't know my size, so I asked the shop staff.
お店 is typically counted with 軒 as a standalone building (一軒のお店), though 店 itself can also appear directly as a counter in casual speech.
Polite form of 店 (みせ) with the honorific prefix お.