you only live once
A proverb encouraging people to seize the moment and live without regret, similar to the English YOLO but more reflective.
You only live once, so let's do what we want to do.
Saying 'you only live once,' he quit his job and set off on a world trip.
Means 'only once' and is the core phrase; 人生は一度きり extends it to a life philosophy.
English loanword used in Japanese with a similar meaning, but more casual and trendy.
A set phrase combining 人生 (life), は (topic marker), 一度 (once), and きり (only). The exact origin is unclear, but it reflects a common sentiment in Japanese culture.