first of all; in the first place; to begin with
Used to emphasize that something is the most fundamental or primary point, often before stating a reason, condition, or important fact. Similar to まず, but stronger and more formal.
First of all, we must solve this problem.
まずもって、彼の努力を認めるべきだ。
In the first place, we should acknowledge his efforts.
Kanji form using 先ず for まず and もって. Seen in formal writing but kana is preferred.
Kanji form with 以て for もって. Rare and somewhat literary.
Combination of まず (first) and もって (emphatic particle, from 持って). The exact historical development is uncertain, but it serves as an intensified form of まず.