office; workroom
A formal term for a room where official duties or business is conducted, such as an executive's office or a government official's office. Often used in official contexts.
The company president met with a visitor in his office.
Important documents are kept in the minister's office.
Compound of 執務 (shitsumu, 'performance of duties') + 室 (shitsu, 'room'). The term is straightforwardly derived from its components.