noun, noun which may take the genitive case particle 'no'
extremely troubled; very puzzled; at a complete loss
Describes a state of being deeply perplexed or greatly distressed, often due to an unexpected problem. Used as a noun or with の to modify another noun.
I'm at a complete loss because of the sudden power outage.
He asked for help with a very troubled look on his face.
Compound of 大 (おお, 'big, great') and 弱り (よわり, 'weakening, trouble'), the noun form of 弱る (よわる, 'to weaken, to be troubled').