noun
one's house; one's home; one's family; one's household
Refers to the speaker's own home or family; the 'one's' nuance is inherent. Often used when talking about one's own place or people.
See also: 内 (うち)
今日はうちでゆっくりします。
I'll relax at home today.
うちの家族
Everyone in my family likes dogs.
noun
A generic 'house' (physical building), without the 'one's own' nuance. This usage is less common and somewhat informal; 家 (いえ) is more standard for a generic house.
あそこに大きいうちがあるね。
There's a big house over there, isn't there?
いえ is the standard word for 'house' as a physical building, while うち emphasizes 'one's own home/family' and is more personal.
The historical derivation is uncertain; うち has been used since Old Japanese to mean 'inside' or 'one's own place', and the kanji 家 is conventionally associated with the meaning of home/family.