Refers to one's own residence, often used in formal or written contexts. In casual speech, 家 (うち/いえ) is more common.
More people are working from home.
彼は自宅の庭で野菜を育てている。
He grows vegetables in his home garden.
Lately, more people work from home.
I stayed home all day today.
After the meeting, I went straight home.
It's a ten-minute walk from my home to the station.
自宅 simply means one's own home with no implication of newness, unlike 新居 which stresses that the home is new.
自宅 means one's own current residence, while 実家 specifically means the home where one's parents live.
自宅 is a formal, slightly bureaucratic word for 'one's own home', while 家 is the everyday, general term for house or home.
持ち家 specifically means a house one owns, whereas 自宅 just means one's own home or residence and can be either owned or rented.
resting at home; home rest
staying at home; self-quarantine; self-isolation · furlough; temporary layoff