Strong, rude imperative telling someone to disappear. Equivalent to 'get lost' or 'fuck off'. Used in anger or extreme annoyance.
See also: 消え失せる
Get lost! Don't ever show your face again.
Shut up and get out of my sight!
Standard kanji spelling for this imperative interjection.
Kana spelling variant; less common but still used.
Imperative form of the verb 消え失せる (to disappear, to vanish).