noun, noun or participle which takes 'suru', intransitive verb, noun which may take the genitive case particle 'no'
A state of losing all hope; can be used as a noun, suru-verb, or adjectivally with の. The suru-verb form is intransitive.
彼は将来に絶望している。
He is in despair about the future.
絶望のあまり、何
I am so hopeless that I can't focus on anything.