Derogatory or condescending plural 'you', used in historical or dramatic speech to address a group of people with contempt.
者ども、覚悟はできているか。
You lot, are you prepared?
people; folks
Plural 'people', often with a slightly rough or old-fashioned tone; not inherently derogatory but can carry a dismissive nuance depending on context.
村の者どもが集まって祭りの準備をした。
The village folks gathered to prepare for the festival.