Often implies prying into others' affairs; can be used as a noun or na-adjective.
His nosy curiosity is a real problem.
Please stop asking prying questions.
My neighbor is a busybody who always asks about other people's business.
Compound of 詮索 (せんさく, 'inquiry, investigation') and 好き (ずき, 'liking, fondness'). The exact historical derivation is uncertain.