expression, godan verb (-u)
be left destitute; be turned out on the street; be rendered homeless
Idiomatic expression meaning to lose one's livelihood or home and end up on the streets, often due to misfortune or financial ruin.
会社が倒産して、彼は路頭に迷った。
His company went bankrupt and he was left destitute.
戦争で家を失い、多くの人が路頭に迷った。
Many people lost their homes in the war and were turned out on the streets.