Refers to soft, disposable paper used for cleaning or in the bathroom. Often implies a somewhat old-fashioned or household term; ティッシュペーパー and トイレットペーパー are more common in modern speech.
My grandmother always keeps tissue paper in the kitchen.
In the old days, people used tissue paper to blow their noses.
He blew his nose with a tissue.
I wrapped the medicine in tissue paper and took it with me.
Katakana variant of the first part; seen in some packaging or informal writing.
Full kanji spelling; rarely used in modern writing.
Kana spelling; common in everyday writing when the kanji is not needed.