A combination of に and は that marks a place, time, recipient, target, or similar に-marked phrase as a topic or point of contrast. Often translates simply as the normal English preposition plus a slight sense of emphasis, such as 'as for there' or 'at least to him.'
See also: に
There is no large hospital in this town.
Used after a dictionary-form verb phrase to introduce what is necessary, suitable, or useful for achieving that action: Vには often means 'in order to V' or 'for V-ing.'
Formal and honorific use that makes a respected person or group the topic, often in set greetings, letters, and very polite speech. It is not just an ordinary topic marker; it helps show respect toward the person being mentioned.
See also: は
indeed ... but; certainly ... but; while it is true that ...
Used in the pattern AにはAが or AにはAけれど, repeating the same word or phrase to concede that something is true before adding a contrast or limitation.
I do want it, but I can't buy it right now.
I have already told him.
In order to pass, you need to study every day.
Solving this problem requires a bit of ingenuity.
I hope that you all have been well.
I am pleased to hear that you are enjoying ever better health, Professor.
I did read it, but I don't remember the contents very well.
に marks direction, location, time, or recipient on its own, while には adds は to make that に-marked element a topic or point of emphasis/contrast.
は is the general topic/contrast particle used after nouns and phrases, whereas には is specifically は attached to に, keeping a locational, temporal, or purposive meaning while adding topic or contrast.
ために explicitly means 'for the sake of' or 'in order to,' while verb + には (as in 合格するには) instead highlights the condition or requirement needed to achieve something.
A transparent particle combination of に plus the topic/contrast particle は. In pronunciation, は is read as わ as a particle, though the written form remains には.