Colloquial, warm term for one's own wife, often used in casual conversation. Can also refer to someone else's wife in friendly speech.
My wife is a good cook.
He finally got married.
I got some vegetables from the wife next door.
My friend is depressed because his wife left him.
家内 is a humble, somewhat formal way to refer to one's own wife in front of others, while 嫁さん is casual and warm.
旦那 refers to a husband, the male counterpart to 嫁さん which refers to a wife.
奥さん is the polite term used for someone else's wife, while 嫁さん is a casual term that can refer to one's own or a close friend's wife.
嫁 can mean either 'wife' or 'daughter-in-law' depending on context, while 嫁さん specifically and casually means 'wife'.
counter for people
wife; bride
Derived from 嫁 (よめ, 'bride, daughter-in-law') with the honorific/polite suffix さん. The shift to meaning 'wife' reflects colloquial usage.