Related words さておき is the core verb form meaning 'setting aside,' while それはさておき is the fuller fixed phrase that explicitly names 'that' as the thing being set aside.
ともかく is a general-purpose 'anyway/in any case' that can start a sentence without referring back to anything, whereas それはさておき specifically dismisses a point just made before returning to the main topic.
それより is a casual way to pivot to a new, often unrelated topic ('more importantly...'), while それはさておき more pointedly sets aside the previous remark to return to the original subject.
閑話休題 is a stiff, literary four-character idiom for returning to the main topic, while それはさておき is the everyday conversational equivalent.
Etymology From それ (that) + は (topic marker) + さておき (setting aside), the continuative form of さておく (to set aside). The phrase is a fixed expression meaning 'putting that aside'.
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