stay-at-home; shut-in; recluse
Describes a person who dislikes going out and prefers to stay at home. Often used as a noun or na-adjective.
He is a stay-at-home and always stays home on weekends.
出嫌いな性格だから、旅行にはあまり行かない。
Because I have a shut-in personality, I don't travel much.
Compound of 出 (で, 'going out') and 嫌い (ぎらい, 'dislike'). The exact historical derivation is uncertain, but the word transparently means 'dislike of going out'.